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Endometriosis and Infertility: What is the Role of Surgery?

Endometriosis and Infertility: What is the Role of Surgery?

We know that endometriosis is associated with infertility and, in patients with deep infiltrating endometriosis (DIE), spontaneous pregnancy rate (without the use of assisted reproduction technologies) is estimated to be around 2 and 10% (1). Although these patients often end up using assisted reproduction in order to get pregnant, can surgical management of endometriosis increase the chances of conception?  …

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Pregnancy in women with Endometriosis

Pregnancy in women with Endometriosis

We have seen that endometriosis is associated with infertility. What is more, we know that the symptoms of the disease, typically, improve during pregnancy. Is the disease, however, associated with direct effects on the pregnancy itself? Unfortunately, in the literature, there is a paucity of high-quality data answering this topic clearly. Τhere have been rare case reports of serious complications…

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What is the cause of Endometriosis?

What is the cause of Endometriosis?

There is no commonly accepted aetiology of the disease. Endometriosis is a complex, heterogeneous and multifactorial disease, in which are involved hormonal, genetic, environmental and immunologic factors. The most likely theories are: What is more, the disease could be associated with the following: In conclusion, it is not very clear what causes endometriosis. It is likely to be a combination…

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What is Endometriosis?

What is Endometriosis?

Endometriosis is the benign disease, where endometrial-like tissue is found in places other than the uterus1. Possible locations include the ovaries, fallopian tubes, peritoneum( the thin membrane that covers the pelvic organs), bowel, urinary tract (urinary bladder and ureters), as well as less common locations (such as nerves, diaphragm, abdominal wall, lungs). This hormone-sensitive disease (sensitive to oestrogens) affects around…

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Endometriosis and ovarian cancer

Endometriosis and ovarian cancer

Endometriosis is a benign disease, however, does its presence increase the risk of ovarian cancer? Or, to ask differently, do ovarian cancers in women with endometriosis arise from the malignant transformation of endometriosis foci or not? A large number of studies has been published on this topic. One of the most interesting has been published recently, indicating that in women…

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Does Endometriosis get worse over time?

Does Endometriosis get worse over time?

It is not clear how the disease evolves with time. In its deep form (DIE), it is likely that endometriosis is a progressive disease (getting progressively worse over time1). This only makes sense, if we accept that large lesions must have developed over a period of time. The rate of progress is unlikely to be fast2, but may vary between…

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