- Endometriosis affects 1 in 10 women of reproductive age, or around 176 million women worldwide1.
- In women with infertility, the frequency of endometriosis can rise to 35-50%2.
- Every year, the disease causes around 70 billion dollars to the healthcare systems3.
- Endometriosis causes a significant loss in the number of working hours, around 11 hours per week per patient4.
- On average, it takes 8 years from the first symptom to diagnosis5.
- Medical management is successful in 2/3rds of patients with endometriosis6.
- A number of women with endometriosis needs surgery. It is estimated that more than 100.000 hysterectomies are done in the United Stated per year due to endometriosis and around 12% of women with endometriosis will need a hysterectomy at some point in their lives7,8.
- The post-operative rate of recurrence is estimated to be higher than 20%9,10.
- Endometriosis, often, coexists with other diseases. Adenomyosis(the presence of endometrium inside the myometrium) coexists in 80 to 90% of women with endometriosis and infertility11.
- It is recognised the significant negative impact of the disease on the psychological health of women with endometriosis12.
References:
- Rogers PA, D’Hooghe TM, Fazleabas A, et al. Priorities for endometriosis research: recommendations from an international consensus workshop. Reprod Sci 2009;16(4):335-46.
- Bulun, SE. Endometriosis. N Engl J Med 2009; 360: 268–279.
- Soliman AM, Surrey E, Bonafede M, Nelson JK, Castelli-Haley J. Real-World Evaluation of Direct and Indirect Economic Burden Among Endometriosis Patients in the United States. Adv Ther. 2018 Mar;35(3):408-423.
- Nnoaham KE, Hummelshoj L, Webster P, d’Hooghe T, de Cicco Nardone F, de Cicco Nardone C, Jenkinson C, Kennedy SH, Zondervan KT; World Endometriosis Research Foundation Global Study of Women’s Health consortium. Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries. Fertil Steril. 2011 Aug;96(2):366-373.e8. doi: 10.1016/j.fertnstert.2011.05.090. Epub 2011 Jun 30.
- ‐Pinto CL. Time elapsed from onset of symptoms to diagnosis of endometriosis in a cohort study of Brazilian women. Hum Reprod 2003;18(4):756-759.
- Donnez J, Dolmans MM. GnRH Antagonists with or without Add-Back Therapy: A New Alternative in the Management of Endometriosis? Int J Mol Sci. 2021 Oct 20;22(21):11342.
- Lepine LA, Hillis SD, Marchbanks PA, et al. Hysterectomy surveillance – United States, 1980-1993. MMWR CDC Surveill Summ. 1997;46:1–15.
- Rizk B, Abdalla H. Fast Facts: Endometriosis. (2nd ed.) Oxford: Health Press; 2003.
- Guo S.W. Recurrence of endometriosis and its control. Hum. Reprod. Update. 2009; 15:441–461.
- Vercellini P., Crosignani1 P.G., Abbiati A., Somigliana E., Viganò P., Fedele L. The effect of surgery for symptomatic endometriosis: The other side of the story. Hum. Reprod. Update. 2009; 15:177–188.
- G. Kunz, D. Beil, P. Huppert, M. Noe, S. Kissler, G. Leyendecker, Adenomyosis in endometriosis—prevalence and impact on fertility. Evidence from magnetic resonance imaging, Human Reproduction, Volume 20, Issue 8, August 2005, Pages 2309–2316.
- Cole JM, Grogan S, Turley E. “The most lonely condition I can imagine”: Psychosocial impacts of endometriosis on women’s identity. Feminism & Psychology. 2021;31(2):171-191.