Vitamin D is a steroid hormone produced mostly as a result of exposure to UV light and regulates the levels of calcium and phosphate in the blood (1). Except its role in bone health, studies have demonstrated its role in human reproduction, with 15% of subfertile couples having low vitamin D levels (2), as well in regulation of inflammation,…
There is no commonly accepted aetiology of the disease. Endometriosis is a complex, heterogeneous and multifactorial disease, in which are involved hormonal, genetic, environmental and immunologic factors. The most likely theories are: What is more, the disease could be associated with the following: In conclusion, it is not very clear what causes endometriosis. It is likely to be a combination…
There is some evidence suggesting that endometriosis is an inherited disease: the risk of disease is 6-9% higher in 1st-degree relatives of women suffering from endometriosis1,2(The risk increases to 15% in cases of severe endometriosis3,4). In twin sisters, the frequency and age of onset of the disease are similar5. However, the identification of the genetic factors associated with the disease…
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