Vitamin D is a steroid hormone produced mostly as a result of exposure to UV light and regulates the levels of calcium and phosphate in the blood (1). Except its role in bone health, studies have demonstrated its role in human reproduction, with 15% of subfertile couples having low vitamin D levels (2), as well in regulation of inflammation,…
Endometriosis is a ‘’hormone-sensitive’’ disease. The disease is ‘’dependent’’ on oestrogens, as we observe raised levels of oestrogens as well as changes in the oestrogen receptors of women with endometriosis1. We also observe ‘’progesterone resistance’’ as a result of dysfunction of its receptors2. Apart from the dependence on oestrogens and the progesterone resistance, patients with endometriosis present higher levels of…
It is not clear how the disease evolves with time. In its deep form (DIE), it is likely that endometriosis is a progressive disease (getting progressively worse over time1). This only makes sense, if we accept that large lesions must have developed over a period of time. The rate of progress is unlikely to be fast2, but may vary between…
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